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Kashi Clinical Laboratories
10101 SW Barbur Blvd, Suite 200
Portland, OR 97219

1 877 879-1815
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Thank you for your interest in Kashi Health's genetic testing services.

Our genetic tests require guidance from a licensed healthcare provider. You may find a qualified provider from our list of approved professionals in the link below, or you may email your provider directly requesting that they contact us to request a genetic test. We wish you the best in your pursuit of healthy living.

1-877-879-1815

Behçet's Disease

Behçet's disease is a systemic inflammatory vasculitis, characterized by a course of remission and relapse of oral ulcers, genital ulcers, skin lesions and ocular lesions.

It can affect the arteries and veins of almost any system and has been shown to involve the gastrointestinal and neurological systems. The cause of Behçet's is unknown but it is believed to be triggered by an infectious or environmental agent in a genetically predisposed individual.

Clinical Utility:

The HLA class I molecule HLA-B51 is the most strongly associated risk factor and has been shown to be associated with Behçet's in Turkish and Asian patients, though the association in Caucasian patients is much weaker.

Testing for HLA-B51 is a useful, though not diagnostic, tool for Behçet's as the vast majority of HLA-B51 carriers do not develop Behçet's. Diagnosis is instead based on the recurrence of symptoms including oral ulcers, genital ulcers, skin lesions and ocular lesions. Treatment options depend on organs involved.

Method:

Kashi Clinical Laboratories utilizes a combination of PCR-SSO (polymerase chain reaction sequence specific oligonucleotide typing) and SBT (sequence based typing) for testing.

Kashi's in-house laboratory and experienced health professionals ensure that customer service is personal, timely, and tailored to every patient's needs.

What is the Next Step? 

Make Kashi Health's Genetic Testing part of your patient's treatment plan today. 

Questions? Please contact our customer service team at 877-879-1815 or 503-206-4989 or by email at This email address is being protected from spambots. You need JavaScript enabled to view it. . We are available Monday through Friday, from 8:00 AM - 5:00 PM, Pacific Time.

 References
  1. Ahmad T et al. Mapping the HLA association in Behçet's disease: a role for tumor necrosis factor polymorphisms? Arthritis Rheum. 2003; 48:807.
  2. de Menthon M et al. HLA-B51/B5 and the risk of Behçet's disease: a systematic review and meta-analysis of case-control genetic association studies. Arthritis Rheum. 2009; 61:1287.
  3. Kötter I et al. Comparative analysis of the association of HLA-B*51 suballeles with Behçet's disease in patients of German and Turkish origin. Tissue Antigens. 2001; 58:166.
  4. Mahr A et al. Population-based prevalence study of Behçet's disease: differences by ethnic origin and low variation by age at immigration. Arthritis Rheum. 2008; 58:3951.
  5. Yazici H et al. Behçet's syndrome is not so rare: why do we need to know? Arthritis Rheum. 2008; 58:3640.